产品名称
RTN2 Rabbit Polyclonal Antibody
蛋白名称
Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (Neuroendocrine-specific protein-like I) (NSP-like protein I) (NSPLI)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O75298
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75298/entry
Mouse Swissprot No.
O70622
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70622
免疫原
Synthesized peptide derived from human protein . at AA range: 391-440
特异性
RTN2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Apr 2012],
组织表达
[Isoform RTN2-C]: Highly expressed in skeletal muscle.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma ; Multi-pass membrane protein . Cell membrane, sarcolemma, T-tubule ; Multi-pass membrane protein . Cytoplasm, myofibril, sarcomere, Z line . Cytoplasm, cytoskeleton . Localizes to intermediate filaments in mononucleated myoblasts and to Z lines in mature myotubes. .
功能
miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.,similarity:Contains 1 reticulon domain.,tissue specificity:Isoform RTN2-C is highly expressed in skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
