产品名称
RTN2 Rabbit Polyclonal Antibody
蛋白名称
Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (Neuroendocrine-specific protein-like I) (NSP-like protein I) (NSPLI)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O75298
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75298/entry
Mouse Swissprot No.
O70622
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70622
免疫原
Synthesized peptide derived from human protein . at AA range: 391-440
特异性
RTN2 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Apr 2012],
组织表达
[Isoform RTN2-C]: Highly expressed in skeletal muscle.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma ; Multi-pass membrane protein . Cell membrane, sarcolemma, T-tubule ; Multi-pass membrane protein . Cytoplasm, myofibril, sarcomere, Z line . Cytoplasm, cytoskeleton . Localizes to intermediate filaments in mononucleated myoblasts and to Z lines in mature myotubes. .
功能
miscellaneous:The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.,similarity:Contains 1 reticulon domain.,tissue specificity:Isoform RTN2-C is highly expressed in skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
