产品名称
PF4V Rabbit Polyclonal Antibody
基因名称
PF4V1 CXCL4V1 SCYB4V1
蛋白名称
Platelet factor 4 variant (C-X-C motif chemokine 4 variant) (CXCL4L1) (PF4alt) (PF4var1) [Cleaved into: Platelet factor 4 variant(4-74); Platelet factor 4 variant(5-74); Platelet factor 4 variant(6-74)]
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P10720
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P10720/entry
免疫原
Synthesized peptide derived from human protein . at AA range: 54-103
特异性
PF4V Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a chemokine that is highly similar to platelet factor 4. The encoded protein displays a strong antiangiogenic function and is regulated by chemokine (C-X-C motif) receptor 3. This protein also impairs tumor growth and can protect against blood-retinal barrier breakdown in diabetes patients. [provided by RefSeq, Nov 2015],
信号通路
Cytokine-cytokine receptor interaction;Chemokine;
功能
function:Inhibitor of angiogenesis. Inhibitor of endothelial cell chemotaxis (in vitro).,mass spectrometry:Platelet factor 4 variant PubMed:15459074,mass spectrometry:Platelet factor 4 variant(4-74) PubMed:15459074,mass spectrometry:Platelet factor 4 variant(5-74) PubMed:15459074,mass spectrometry:Platelet factor 4 variant(6-74) PubMed:15459074,PTM:The N-terminal processed forms of platelet factor 4 variant seems to be produced by proteolytic cleavage. The most abundant form is Platelet factor 4 variant(5-74).,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
