产品名称
ID3 Rabbit Polyclonal Antibody
基因名称
ID3 1R21 BHLHB25 HEIR1
蛋白名称
DNA-binding protein inhibitor ID-3 (Class B basic helix-loop-helix protein 25) (bHLHb25) (Helix-loop-helix protein HEIR-1) (ID-like protein inhibitor HLH 1R21) (Inhibitor of DNA binding 3)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q02535
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q02535/entry
Mouse Swissprot No.
P41133
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P41133
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P41138
免疫原
Synthesized peptide derived from human protein . at AA range: 68-117
特异性
ID3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts. [provided by RefSeq, Aug 2011],
组织表达
Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain.
功能
function:ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors.,induction:By phorbol 12-myristate 13-acetate (PMA).,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Interacts with COPS5 and COPS7A (By similarity). Homodimer, and heterodimer with other HLH proteins.,tissue specificity:Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
