产品名称
AOFB Rabbit Polyclonal Antibody
蛋白名称
Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P27338
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P27338/entry
Mouse Swissprot No.
Q8BW75
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BW75
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P19643
免疫原
Synthesized peptide derived from human protein . at AA range: Internal
特异性
AOFB Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.
信号通路
Glycine; serine and threonine metabolism;Arginine and proline metabolism;Histidine metabolism;Tyrosine metabolism;Phenylalanine metabolism;Tryptophan metabolism;Drug metabolism;
功能
catalytic activity:RCH(2)NHR' + H(2)O + O(2) = RCHO + R'NH(2) + H(2)O(2).,cofactor:FAD.,function:Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.,mass spectrometry: PubMed:11049757,online information:Monoamine oxidase entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the flavin monoamine oxidase family.,subunit:Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
