产品名称
CHODL Rabbit Polyclonal Antibody
基因名称
CHODL C21orf68 PRED12 UNQ872/PRO1890
蛋白名称
Chondrolectin (Transmembrane protein MT75)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H9P2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H9P2/entry
Mouse Swissprot No.
Q9CXM0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CXM0
免疫原
Synthesized peptide derived from human protein . at AA range: 140-220
特异性
CHODL Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Feb 2011],
组织表达
Found in spleen, testis, prostate and fetal liver. Expression limited to vascular muscle of testis, smooth muscle of prostate stroma, heart muscle, skeletal muscle, crypts of small intestine, and red pulp of spleen. B lymphocytes express isoform 2 only; peripheral blood T lymphocytes express isoform 3 only; granulocytes and monocytes express neither isoform 2 nor isoform 3. During development of T lymphocytes, bone marrow progenitor cells express isoform 2 only; thymocytes at different stages of maturation express predominantly isoform 2 and weakly isoform 3, and mature thymocytes express only isoform 2.
细胞定位
Cytoplasm . Membrane ; Single-pass type I membrane protein .; [Isoform 2]: Endoplasmic reticulum . Endoplasmic reticulum membrane ; Single-pass type I membrane protein .; [Isoform 3]: Cytoplasm .
功能
online information:Chondrolectin,PTM:N-glycosylated.,similarity:Contains 1 C-type lectin domain.,tissue specificity:Found in spleen, testis, prostate and fetal liver. Expression limited to vascular muscle of testis, smooth muscle of prostate stroma, heart muscle, skeletal muscle, crypts of small intestine, and red pulp of spleen.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
