产品名称
SPON1 Rabbit Polyclonal Antibody
蛋白名称
Spondin-1 (F-spondin) (Vascular smooth muscle cell growth-promoting factor)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9HCB6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9HCB6/entry
Mouse Swissprot No.
Q8VCC9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8VCC9
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P35446
免疫原
Synthesized peptide derived from human protein . at AA range: 210-290
特异性
SPON1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell.,similarity:Contains 1 reelin domain.,similarity:Contains 1 spondin domain.,similarity:Contains 6 TSP type-1 domains.,subunit:Binds to the central extracellular domain of APP and inhibits beta-secretase cleavage of APP.,tissue specificity:Highest expression in lung, lower expression in brain, heart, kidney, liver and testis, and lowest expression in pancreas, skeletal muscle and ovary. Not expressed in spleen.,
组织表达
Highest expression in lung, lower expression in brain, heart, kidney, liver and testis, and lowest expression in pancreas, skeletal muscle and ovary. Not expressed in spleen.
细胞定位
Secreted, extracellular space, extracellular matrix .
功能
function:Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell.,similarity:Contains 1 reelin domain.,similarity:Contains 1 spondin domain.,similarity:Contains 6 TSP type-1 domains.,subunit:Binds to the central extracellular domain of APP and inhibits beta-secretase cleavage of APP.,tissue specificity:Highest expression in lung, lower expression in brain, heart, kidney, liver and testis, and lowest expression in pancreas, skeletal muscle and ovary. Not expressed in spleen.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
