产品名称
PARPT Rabbit Polyclonal Antibody
蛋白名称
TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q7Z3E1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7Z3E1/entry
Mouse Swissprot No.
Q8C1B2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8C1B2
免疫原
Synthesized peptide derived from human protein . at AA range: 450-530
特异性
PARPT Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
组织表达
Brain,Endometrial tumor,Testis,
功能
catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,function:Poly [ADP-ribose] polymerase using NAD(+) as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.,similarity:Contains 1 C3H1-type zinc finger.,similarity:Contains 1 PARP catalytic domain.,similarity:Contains 1 WWE domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
