产品名称
FABP6 Rabbit Polyclonal Antibody
蛋白名称
Gastrotropin (GT) (Fatty acid-binding protein 6) (Ileal lipid-binding protein) (ILBP) (Intestinal 15 kDa protein) (I-15P) (Intestinal bile acid-binding protein) (I-BABP)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P51161
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P51161/entry
Mouse Swissprot No.
P51162
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P51162
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P80020
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
FABP6 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level).
细胞定位
[Isoform 1]: Cytoplasm . Membrane; Peripheral membrane protein ; Cytoplasmic side .; [Isoform 2]: Cytoplasm . Localized close to nucleus on the apical side of both normal and neoplastic cells. .
功能
domain:Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.,function:Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
