产品名称
H6ST2 Rabbit Polyclonal Antibody
蛋白名称
Heparan-sulfate 6-O-sulfotransferase 2 (HS6ST-2) (EC 2.8.2.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q96MM7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96MM7/entry
Mouse Swissprot No.
Q80UW0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q80UW0
免疫原
Synthesized peptide derived from human protein . at AA range: 140-220
特异性
H6ST2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Heparan sulfate proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various ligands to influence cell growth, differentiation, adhesion, and migration. This gene encodes a member of the heparan sulfate (HS) sulfotransferase gene family, which catalyze the transfer of sulfate to HS. Different family members and isoforms are thought to synthesize heparan sulfates with tissue-specific structures and functions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Amygdala,Brain,Placenta,
细胞定位
Membrane ; Single-pass type II membrane protein .
信号通路
Heparan sulfate biosynthesis;
功能
catalytic activity:3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 6-sulfate.,function:6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.,similarity:Belongs to the sulfotransferase 6 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
