产品名称
AMGO1 Rabbit Polyclonal Antibody
基因名称
AMIGO1 ALI2 AMIGO KIAA1163
蛋白名称
Amphoterin-induced protein 1 (AMIGO-1) (Alivin-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q86WK6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q86WK6/entry
Mouse Swissprot No.
Q80ZD8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q80ZD8
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q80ZD7
免疫原
Synthesized peptide derived from human protein . at AA range: 120-200
特异性
AMGO1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain.,similarity:Belongs to the immunoglobulin superfamily. AMIGO family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subcellular location:Associated with axons of neuronal cells.,subunit:Binds itself as well as AMIGO2 and AMIGO3.,
组织表达
Brain,Hippocampus,Monocytic leukemia,Ovary,
细胞定位
Cell membrane ; Single-pass type I membrane protein . Perikaryon . Cell projection, dendrite . Cell projection, axon . Colocalizes with KCNB1 at high-density somatodendritic clusters on the surface of hippocampal and cortical neurons. Associated with axons of neuronal cells. .
功能
function:Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain.,similarity:Belongs to the immunoglobulin superfamily. AMIGO family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subcellular location:Associated with axons of neuronal cells.,subunit:Binds itself as well as AMIGO2 and AMIGO3.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
