产品名称
PGS1 Rabbit Polyclonal Antibody
蛋白名称
Biglycan (Bone/cartilage proteoglycan I) (PG-S1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P21810
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P21810/entry
Mouse Swissprot No.
P28653
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P28653
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P47853
免疫原
Synthesized peptide derived from human protein . at AA range: 110-190
特异性
PGS1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015],
组织表达
Found in several connective tissues, especially in articular cartilages.
细胞定位
Secreted, extracellular space, extracellular matrix .
功能
function:May be involved in collagen fiber assembly.,PTM:The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate.,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class I subfamily.,similarity:Contains 12 LRR (leucine-rich) repeats.,subunit:Homodimer. Forms a ternary complex with MFAP2 and ELN.,tissue specificity:Found in several connective tissues, especially in articular cartilages.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
