产品名称
PILRB Rabbit Polyclonal Antibody
蛋白名称
Paired immunoglobulin-like type 2 receptor beta (Activating receptor PILR-beta) (Cell surface receptor FDFACT)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UKJ0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UKJ0/entry
Mouse Swissprot No.
Q2YFS2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q2YFS2
免疫原
Synthesized peptide derived from human protein . at AA range: 170-250
特异性
PILRB Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function. [provided by RefSeq, Jun 2013],
组织表达
Peripheral blood leukocyte,Spleen,Testis,
细胞定位
Membrane ; Single-pass type I membrane protein .
功能
function:Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
