BD-PN2362

MEPE Rabbit Polyclonal Antibody

常规抗体

MEPE

Matrix extracellular phosphoglycoprotein (Osteoblast/osteocyte factor 45) (OF45)

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

56955

Q9NQ76

https://www.uniprot.org/uniprotkb/Q9NQ76/entry

Synthesized peptide derived from human protein . at AA range: 20-100

MEPE Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

57kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging-related trabecular bone loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],

Expressed by osteoblasts (PubMed:10945470, PubMed:11414762, PubMed:15108058). Expressed by stem cells in dental pulp (PubMed:15153459). Expressed by mesenchymal cells in dental papilla and dental pulp (PubMed:18547474, PubMed:22341070). Expressed in teeth, specifically in decidious dentin (PubMed:20581062). Expressed in ondotoblasts (PubMed:12489176). Expressed in salivary glands (PubMed:15329369). Secreted from oncogenic hypophosphatemic tumors (PubMed:11414762).

Secreted, extracellular space, extracellular matrix .

function:Seems to play a role in mineralization.,tissue specificity:Expressed by osteoblasts. Secreted from oncogenic hypophosphataemic tumours.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.