产品名称
WNT2 Rabbit Polyclonal Antibody
蛋白名称
Protein Wnt-2 (Int-1-like protein 1) (Int-1-related protein) (IRP)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P09544
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P09544/entry
Mouse Swissprot No.
P21552
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P21552
免疫原
Synthesized peptide derived from human protein . at AA range: 200-280
特异性
WNT2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the WNT gene family. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008],
组织表达
Expressed in brain in the thalamus, in fetal and adult lung and in placenta.
细胞定位
Secreted, extracellular space, extracellular matrix . Secreted .
信号通路
WNT;WNT-T CELLHedgehog;Melanogenesis;Pathways in cancer;Basal cell carcinoma;
功能
function:Ligand for members of the frizzled family of seven transmembrane receptors.,function:Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.,similarity:Belongs to the Wnt family.,tissue specificity:Expressed in brain in the thalamus, in fetal and adult lung and in placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
