产品名称
GLRX1 Rabbit Polyclonal Antibody
蛋白名称
Glutaredoxin-1 (Thioltransferase-1) (TTase-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P35754
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P35754/entry
Mouse Swissprot No.
Q9QUH0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9QUH0
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9ESH6
免疫原
Synthesized peptide derived from human protein . at AA range: 40-120
特异性
GLRX1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011],
组织表达
Blood,Brain,Lens,Liver,Skin,Spleen,Urinary bladder,
功能
function:Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.,similarity:Belongs to the glutaredoxin family.,similarity:Contains 1 glutaredoxin domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
