产品名称
SLIK4 Rabbit Polyclonal Antibody
蛋白名称
SLIT and NTRK-like protein 4
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8IW52
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8IW52/entry
Mouse Swissprot No.
Q810B8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q810B8
免疫原
Synthesized peptide derived from human protein . at AA range: 130-210
特异性
SLIK4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
组织表达
Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, glioblastomas and primitive neuroectodermal tumors.
细胞定位
Membrane ; Single-pass type I membrane protein . Cell membrane .
功能
function:Suppresses neurite outgrowth.,similarity:Belongs to the SLITRK family.,similarity:Contains 18 LRR (leucine-rich) repeats.,tissue specificity:Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, gliobastomas and primitive neuroectodermal tumors.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
