产品名称
TRML2 Rabbit Polyclonal Antibody
基因名称
TREML2 C6orf76 TLT2 UNQ6268/PRO20473
蛋白名称
Trem-like transcript 2 protein (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q5T2D2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q5T2D2/entry
Mouse Swissprot No.
Q2LA85
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q2LA85
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
TRML2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).[supplied by OMIM, Mar 2008],
组织表达
Detected in cultured B-cells, T-cell leukemia and monocyte leukemia. Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
function:Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counterreceptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation.,induction:Induced in CD4 T-cells by concanavalin A.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD276 and this interaction enhances T-cell activation.,tissue specificity:Detected in cultured B cells, T cell leukemia and monocyte leukemia. Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
