产品名称
SEM6A Rabbit Polyclonal Antibody
基因名称
SEMA6A KIAA1368 SEMAQ
蛋白名称
Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H2E6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H2E6/entry
Mouse Swissprot No.
O35464
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35464
免疫原
Synthesized peptide derived from human protein . at AA range: 430-510
特异性
SEM6A Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011],
组织表达
Brain,Hypothalamus,Placenta,
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
function:Can act as repulsive axon guidance cues. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,subunit:Active as a homodimer or oligomer. Interacts with EVL.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.