BD-PE5371

PANK2 (3N17) Mouse Monoclonal antibody

常规抗体

PANK2

WB

Human,Mouse,Rat

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Full length human recombinant protein of human PANK2 (NP_705902) produced in HEK293T cell.

WB 1:2000, IF 1:100, FCM 1:100

59.1kDa

-20°C/1 year

Mouse

IgG1

This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)