BD-PE5346

UHRF2 (16Z9) Mouse Monoclonal antibody

常规抗体

NIRF

WB

Human,Mouse,Rat

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Human recombinant protein fragment corresponding to amino acids 1-288 of human UHRF2(NP_690856) produced in E.coli.

WB 1:500~2000

89.8kDa

-20°C/1 year

Mouse

IgG2a

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)