产品名称
NANO2 Rabbit Polyclonal Antibody
蛋白名称
Nanos homolog 2 (NOS-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P60321
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P60321/entry
Mouse Swissprot No.
P60322
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P60322
免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
NANO2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
domain:The Nanos-type zinc finger is composed of two C2HC motifs, each motif binding one molecule of zinc. It is essential for the translation repression activity of the protein.,function:Required to support proliferation and self-renewal of proximal germ cells in males only. Probably regulates translation of specific mRNAs by associating with the 3'-UTR of mRNA targets. Essential for spermatogonia formation.,similarity:Belongs to the nanos family.,similarity:Contains 1 nanos-type zinc finger.,
组织表达
Testis and ovary. Expression found in several spermatogenic stages: in cells on the periphery of the tubules which could correspond to spermatogonia, in spermatocytes and in round spermatids (at protein level).
细胞定位
Cytoplasm . Cytoplasm, P-body . Cytoplasm, perinuclear region . Localizes at P-bodies during gonocyte development (By similarity). More abundant in perinuclear region of the cytoplasm of the germ cells of the adult testis. .
功能
domain:The Nanos-type zinc finger is composed of two C2HC motifs, each motif binding one molecule of zinc. It is essential for the translation repression activity of the protein.,function:Required to support proliferation and self-renewal of proximal germ cells in males only. Probably regulates translation of specific mRNAs by associating with the 3'-UTR of mRNA targets. Essential for spermatogonia formation.,similarity:Belongs to the nanos family.,similarity:Contains 1 nanos-type zinc finger.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
