产品名称
CRHBP Rabbit Polyclonal Antibody
蛋白名称
Corticotropin-releasing factor-binding protein (CRF-BP) (CRF-binding protein) (Corticotropin-releasing hormone-binding protein) (CRH-BP)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P24387
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P24387/entry
Mouse Swissprot No.
Q60571
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q60571
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P24388
免疫原
Synthesized peptide derived from human protein . at AA range: 70-150
特异性
CRHBP Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008],
组织表达
Hippocampus,Kidney,Liver,
功能
function:Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.