BD-PE5287

BEST3 (Bestrophin 3) (14U8) Mouse Monoclonal antibody

常规抗体

BEST3

WB

Human,Mouse,Rat

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Full length human recombinant protein of human BEST3 (NP_689652) produced in HEK293T cell.

WB 1:2000, IF 1:100, FCM 1:100

50.8kDa

-20°C/1 year

Mouse

IgG2a

BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]). [supplied by OMIM]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)