产品名称
SEM6A Rabbit Polyclonal Antibody
基因名称
SEMA6A KIAA1368 SEMAQ
蛋白名称
Semaphorin-6A (Semaphorin VIA) (Sema VIA) (Semaphorin-6A-1) (SEMA6A-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H2E6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H2E6/entry
Mouse Swissprot No.
O35464
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35464
免疫原
Synthesized peptide derived from human protein . at AA range: 430-510
特异性
SEM6A Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011],
组织表达
Brain,Hypothalamus,Placenta,
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
function:Can act as repulsive axon guidance cues. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,subunit:Active as a homodimer or oligomer. Interacts with EVL.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.