产品名称
NADL2 Rabbit Polyclonal Antibody
蛋白名称
Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 (NAALADase L2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q58DX5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q58DX5/entry
免疫原
Synthesized peptide derived from human protein . at AA range: 190-270
特异性
NADL2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
caution:Although related to the peptidase M28 family, it is probably inactive as an hydrolase due to lack of the conserved zinc-binding and active sites.,function:May be catalytically inactive.,miscellaneous:The gene maps to 3q26.31, a region associated with Cornelia de Lange syndrome. However, PubMed:15168106 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome.,sequence caution:Contaminating sequence at the C-terminus.,similarity:Belongs to the peptidase M28 family. M28B subfamily.,tissue specificity:Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.,
组织表达
Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.
细胞定位
Membrane ; Single-pass type II membrane protein .
功能
caution:Although related to the peptidase M28 family, it is probably inactive as an hydrolase due to lack of the conserved zinc-binding and active sites.,function:May be catalytically inactive.,miscellaneous:The gene maps to 3q26.31, a region associated with Cornelia de Lange syndrome. However, PubMed:15168106 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome.,sequence caution:Contaminating sequence at the C-terminus.,similarity:Belongs to the peptidase M28 family. M28B subfamily.,tissue specificity:Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
