产品名称
SMAGP Rabbit Polyclonal Antibody
蛋白名称
Small cell adhesion glycoprotein (Small transmembrane and glycosylated protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q0VAQ4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q0VAQ4/entry
Mouse Swissprot No.
Q99KC7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99KC7
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q7TPF1
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
SMAGP Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation.,PTM:O-glycosylated. The O-glycan is modified with sialic acid residues.,similarity:Belongs to the SMAGP family.,subcellular location:Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors.,tissue specificity:Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level).,
组织表达
Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level).
细胞定位
Cell membrane ; Single-pass type III membrane protein . Cytoplasmic vesicle membrane ; Single-pass type III membrane protein . Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions (PubMed:15021913). Detected on cytoplasmic membranes in undifferentiated tumors (PubMed:15986429). .
功能
function:May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation.,PTM:O-glycosylated. The O-glycan is modified with sialic acid residues.,similarity:Belongs to the SMAGP family.,subcellular location:Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors.,tissue specificity:Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
