产品名称
HGFL Rabbit Polyclonal Antibody
基因名称
MST1 D3F15S2 DNF15S2 HGFL
蛋白名称
Hepatocyte growth factor-like protein (Macrophage stimulatory protein) (Macrophage-stimulating protein) (MSP) [Cleaved into: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain]
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P26927
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P26927/entry
Mouse Swissprot No.
P26928
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P26928
免疫原
Synthesized peptide derived from human protein . at AA range: 420-500
特异性
HGFL Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds. [provided by RefSeq, Jan 2010],
组织表达
Liver,Plasma,Testis,
功能
function:Probably has no proteolytic activity, since crucial characteristic of serine proteases catalytic sites are not conserved.,PTM:May be cleaved after Arg-483, to yield two chains held together by disulfide bonds, or two separate polypeptides.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Plasminogen subfamily.,similarity:Contains 1 PAN domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 4 kringle domains.,subunit:Dimer of an alpha chain and a beta chain linked by a disulfide bond.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.