产品名称
UPP2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/151531
Human Swissprot No.
O95045
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95045/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/76654
Mouse Swissprot No.
Q8CGR7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CGR7
免疫原
Synthesized peptide derived from human UPP2 AA range: 164-214
特异性
This antibody detects endogenous levels of UPP2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
组织表达
Predominantly expressed in kidney.
细胞定位
cytoplasm,cytosol,type III intermediate filament,
功能
catalytic activity:Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.,function:Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.,pathway:Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.,similarity:Belongs to the PNP/UDP phosphorylase family.,tissue specificity:Predominantly expressed in kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
