产品名称
TBX6 Rabbit Polyclonal Antibody
蛋白名称
T-box transcription factor TBX6 (T-box protein 6)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O95947
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95947/entry
Mouse Swissprot No.
P70327
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P70327
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941D3ZJK7
免疫原
Synthesized peptide derived from human protein . at AA range: 230-310
特异性
TBX6 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures. [provided by RefSeq, Aug 2008],
组织表达
Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus.
功能
developmental stage:Expressed during gastrulation and during a second phase in some adult tissues.,function:Probable transcriptional regulator involved in developmental processes. Could be required for specification of paraxial mesoderm structures during gastrulation.,similarity:Contains 1 T-box DNA-binding domain.,subunit:Forms a dimeric complex with DNA (in vitro).,tissue specificity:Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
