产品名称
R4RL2 Rabbit Polyclonal Antibody
蛋白名称
Reticulon-4 receptor-like 2 (Nogo receptor-like 3) (Nogo-66 receptor homolog 1) (Nogo-66 receptor-related protein 2) (NgR2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q86UN3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q86UN3/entry
Mouse Swissprot No.
Q7M6Z0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7M6Z0
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q80WD1
免疫原
Synthesized peptide derived from human protein . at AA range: 290-370
特异性
R4RL2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.,PTM:Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein.,similarity:Belongs to the Nogo receptor family.,similarity:Contains 8 LRR (leucine-rich) repeats.,subcellular location:Localized to the surface of neurons, including axons.,tissue specificity:Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.,
组织表达
Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.
细胞定位
Cell membrane ; Lipid-anchor, GPI-anchor . Membrane raft . Cell projection, dendrite . Perikaryon . Cell projection, axon . Localized to the surface of neurons, including axons. Detected close to synapses, but is excluded from synapses. .
功能
function:May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.,PTM:Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein.,similarity:Belongs to the Nogo receptor family.,similarity:Contains 8 LRR (leucine-rich) repeats.,subcellular location:Localized to the surface of neurons, including axons.,tissue specificity:Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
