产品名称
HRK Rabbit Polyclonal Antibody
蛋白名称
Activator of apoptosis harakiri (BH3-interacting domain-containing protein 3) (Neuronal death protein DP5)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O00198
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O00198/entry
Mouse Swissprot No.
P62816
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P62816
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P62817
免疫原
Synthesized peptide derived from part region of human protein AA range: 1-50
特异性
HRK Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
harakiri, BCL2 interacting protein(HRK) Homo sapiens This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],
细胞定位
Membrane; Single-pass membrane protein. Mitochondrion.
功能
domain:The BH3 motif is required for the induction of cell death.,function:Activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
