BD-PE4641

TBL1XR1 (1R3) Mouse Monoclonal antibody

常规抗体

TBL1XR1

WB

Human,Rat,Mouse

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Full length human recombinant protein of human TBL1XR1 (NP_078941) produced in E.coli.

WB 1:500~2000

55.4kDa

-20°C/1 year

Mouse

IgG1

This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)