产品名称
NR6A1 Rabbit Polyclonal Antibody
蛋白名称
Nuclear receptor subfamily 6 group A member 1 (Germ cell nuclear factor) (GCNF) (hGCNF) (Retinoid receptor-related testis-specific receptor) (RTR) (hRTR)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q15406
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q15406/entry
Mouse Swissprot No.
Q64249
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q64249
免疫原
Synthesized peptide derived from human protein . at AA range: 70-150
特异性
NR6A1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2013],
组织表达
Shows highest expression in the germ cells of the adult testis.
功能
function:Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis.,similarity:Belongs to the nuclear hormone receptor family. NR6 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Homodimer. Interacts with UIMC1.,tissue specificity:Shows highest expression in the germ cells of the adult testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
