产品名称
DKKL1 Rabbit Polyclonal Antibody
基因名称
DKKL1 SGY1 UNQ735/PRO1429
蛋白名称
Dickkopf-like protein 1 (Cancer/testis antigen 34) (CT34) (Protein soggy-1) (SGY-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UK85
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UK85/entry
Mouse Swissprot No.
Q9QZL9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9QZL9
免疫原
Synthesized peptide derived from human protein . at AA range: 50-130
特异性
DKKL1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2010],
组织表达
More highly expressed in adult testis than in fetal testis. Exclusively expressed in the testis (at protein level). Intense expression in stages II, III and IV of spermatogenesis, whereas expression is lower in stage I.
细胞定位
Secreted . Cytoplasmic vesicle, secretory vesicle, acrosome . Localized specifically to the crescent shaped acrosome at the apex of the sperm head. .
功能
PTM:N-glycosylated.,similarity:To the N-terminal section of DKK-3.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
