产品名称
BMPER Rabbit Polyclonal Antibody
蛋白名称
BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8N8U9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8N8U9/entry
Mouse Swissprot No.
Q8CJ69
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8CJ69
免疫原
Synthesized peptide derived from human protein . at AA range: 440-520
特异性
BMPER Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis. [provided by RefSeq, Dec 2011],
组织表达
Highly expressed in lung, and brain and also in primary chondrocytes.
功能
function:Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes.,similarity:Contains 1 TIL (trypsin inhibitory-like) domain.,similarity:Contains 1 VWFD domain.,similarity:Contains 5 VWFC domains.,subunit:Interacts with BMP4.,tissue specificity:Highly expressed in lung, and brain and also in primary chondrocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
