BD-PE4444

ALX4 (19U8) Mouse Monoclonal antibody

常规抗体

ALX4

WB

Human,Mouse,Rat

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Full length human recombinant protein of human ALX4(NP_068745) produced in HEK293T cell.

Validated through 10k CHIP testing，using a High-Density Protein Microarray that was spotted with ~17,000 various over-expressed proteins to test for antibody specificity.

IHC 1:100~200

44.1kDa

-20°C/1 year

Mouse

IgG1

This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq, Oct 2009]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)