产品名称
VSIG4 Rabbit Polyclonal Antibody
基因名称
VSIG4 CRIg Z39IG UNQ317/PRO362
蛋白名称
V-set and immunoglobulin domain-containing protein 4 (Protein Z39Ig)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9Y279
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y279/entry
免疫原
Synthesized peptide derived from human protein . at AA range: 70-150
特异性
VSIG4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
组织表达
Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta. Expressed in resting macrophages.
细胞定位
Membrane ; Single-pass type I membrane protein .
功能
function:Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,tissue specificity:Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta. Expressed in resting macrophages.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
