BD-PN2234

LUM Rabbit Polyclonal Antibody

常规抗体

LUM LDC SLRR2D

Lumican (Keratan sulfate proteoglycan lumican) (KSPG lumican)

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

4060

P51884

https://www.uniprot.org/uniprotkb/P51884/entry

P51885

http://www.uniprot.org/uniprot/P51885

P51886

http://www.uniprot.org/uniprot/O54941P51886

Synthesized peptide derived from human protein . at AA range: 30-110

LUM Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

37kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008],

Cornea and other tissues.

Secreted, extracellular space, extracellular matrix .

developmental stage:Present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan.,PTM:Sulfated on tyrosine residue(s).,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class II subfamily.,similarity:Contains 12 LRR (leucine-rich) repeats.,subunit:Binds to laminin.,tissue specificity:Cornea and other tissues.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.