产品名称
BOC Rabbit Polyclonal Antibody
蛋白名称
Brother of CDO (Protein BOC)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9BWV1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BWV1/entry
Mouse Swissprot No.
Q6AZB0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6AZB0
免疫原
Synthesized peptide derived from human protein . at AA range: 630-710
特异性
BOC Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the immunoglobulin/fibronectin type III repeat family. It is a component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells, and promotes myogenic differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014],
组织表达
Detected in skeletal muscle, heart, thymus, kidney and small intestine. Detected at lower levels in brain, placenta, lung and colon mucosa.
细胞定位
Cell membrane ; Single-pass type I membrane protein . Enriched at sites of cell-cell contact.
功能
function:Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.,miscellaneous:The C-terminal cytoplasmic domain is not required for the stimuation of myogenesis.,PTM:N-glycosylated.,similarity:Contains 3 fibronectin type-III domains.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Enriched at sites of cell-cell contact.,subunit:Part of a complex that contains BOC, CDON, NEO1, cadherins and CTNNB1. Interacts with NTN3 (By similarity). Interacts with CDH2 and CTNNB1. Interacts with CDH15 only during the early stages of myoblast differentiation.,tissue specificity:Detected in skeletal muscle, heart, thymus, kidney and small intestine. Detected at lower levels in brain, placenta, lung and colon mucosa.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
