BD-PE4351

RET (11G17) Mouse Monoclonal antibody

常规抗体

RET

WB

Human,Rat

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Human recombinant protein fragment corresponding to amino acids 713-1017 of human RET(NP_066124) produced in E.coli.

WB 1:2000

124.1kDa

-20°C/1 year

Mouse

IgG1

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)