产品名称
NINJ1 Rabbit Polyclonal Antibody
蛋白名称
Ninjurin-1 (Nerve injury-induced protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q92982
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92982/entry
Mouse Swissprot No.
O70131
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70131
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P70617
免疫原
Synthesized peptide derived from part region of human protein. AA range 1-56
特异性
NINJ1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009],
组织表达
Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin.
细胞定位
[Ninjurin-1]: Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptic cell membrane ; Multi-pass membrane protein .; [Secreted ninjurin-1]: Secreted .
功能
function:Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations.,induction:By nerve injury both in dorsal root ganglion neurons and in Schwann cells.,similarity:Belongs to the ninjurin family.,tissue specificity:Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
