产品名称
CLC4D Rabbit Polyclonal Antibody
蛋白名称
C-type lectin domain family 4 member D (C-type lectin superfamily member 8) (C-type lectin-like receptor 6) (CLEC-6)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8WXI8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WXI8/entry
Mouse Swissprot No.
Q9Z2H6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9Z2H6
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q69FH1
免疫原
Synthesized peptide derived from part region of human protein
特异性
CLC4D Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008],
组织表达
Expressed weakly in peripheral blood leukocytes, bone marrow and spleen. Expression is confined mostly in monocytes and macrophage and seems to be up-regulated by IL-6, IL-10, TNF-alpha and IFN-gamma.
细胞定位
Cell membrane ; Single-pass type II membrane protein .
功能
function:Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T cells.,induction:Induced by autocrine inflammatory stimuli.,online information:MCL,similarity:Contains 1 C-type lectin domain.,tissue specificity:Expressed weakly in peripheral blood leukocytes, bone marrow and spleen. Expression is confined mostly in monocytes and macrophage and seems to be up-regulated by IL-6, IL-10, TNF-alpha and IFN-gamma.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
