产品名称
NINJ1 Rabbit Polyclonal Antibody
蛋白名称
Ninjurin-1 (Nerve injury-induced protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q92982
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92982/entry
Mouse Swissprot No.
O70131
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70131
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P70617
免疫原
Synthesized peptide derived from part region of human protein. AA range 1-56
特异性
NINJ1 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009],
组织表达
Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin.
细胞定位
[Ninjurin-1]: Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptic cell membrane ; Multi-pass membrane protein .; [Secreted ninjurin-1]: Secreted .
功能
function:Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations.,induction:By nerve injury both in dorsal root ganglion neurons and in Schwann cells.,similarity:Belongs to the ninjurin family.,tissue specificity:Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
