产品名称
FOLR1 (9Y18) Mouse Monoclonal antibody
基因名称
Folate Binding Protein
存储缓冲液
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
免疫原
Human recombinant protein fragment of Human FOLR1 (NP_057937) produced in Ecoli.
背景介绍
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
纯化
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)