产品名称
ROBO4 Rabbit Polyclonal Antibody
基因名称
ROBO4 UNQ421/PRO3674
蛋白名称
Roundabout homolog 4 (Magic roundabout)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8WZ75
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WZ75/entry
Mouse Swissprot No.
Q8C310
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8C310
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q80W87
免疫原
Synthesized peptide derived from part region of human protein
特异性
ROBO4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins.,similarity:Belongs to the immunoglobulin superfamily. ROBO family.,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with SLIT2 and ENAH.,tissue specificity:Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.,
组织表达
Specifically expressed in endothelial cells. Expressed in endothelial and intimal cells of the ascending aorta (PubMed:30455415).
细胞定位
integral component of membrane,extracellular exosome,
功能
function:Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins.,similarity:Belongs to the immunoglobulin superfamily. ROBO family.,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with SLIT2 and ENAH.,tissue specificity:Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.