产品名称
TXLNG Rabbit Polyclonal Antibody
基因名称
TXLNG CXorf15 ELRG LSR5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55787
Human Swissprot No.
Q9NUQ3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NUQ3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/353170
Mouse Swissprot No.
Q8BHN1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BHN1
免疫原
Synthesized peptide derived from human TXLNG AA range: 219-269
特异性
This antibody detects endogenous levels of TXLNG at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],
组织表达
Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. Expressed in brain, placenta, lung, liver, kidney and pancreas.
细胞定位
Nucleus membrane . Cytoplasm, cytosol .
功能
function:May be involved in intracellular vesicle traffic.,similarity:Belongs to the taxilin family.,subunit:Binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A and STX4A.,tissue specificity:Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. Expressed in brain, placenta, lung, liver, kidney and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
