BD-PE3619

LATS2 (5B18) Mouse Monoclonal antibody

常规抗体

LATS2

WB

Human,Mouse,Rat

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

Human recombinant protein fragment corresponding to amino acids 1-237 of human LATS2 (NP_055387) produced in E.coli.

WB 1:2000

120kDa

-20°C/1 year

Mouse

IgG1

This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]

现货

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)