产品名称
AMPM1 Rabbit Polyclonal Antibody
蛋白名称
Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (EC 3.4.11.18) (Peptidase M 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P53582
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P53582/entry
Mouse Swissprot No.
Q8BP48
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BP48
免疫原
Synthesized peptide derived from part region of human protein
特异性
AMPM1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.,cofactor:Binds 1 sodium ion per subunit. The sodium ion has a structural role.,cofactor:Binds 2 cobalt ions per subunit.,cofactor:Binds 2 cobalt ions per subunit. The true nature of the physiological cofactor is under debate. The enzyme is also active with zinc, manganese or divalent iron ions.,function:Removes the amino-terminal methionine from nascent proteins.,function:Removes the amino-terminal methionine from nascent proteins. Required for normal progression through the cell cycle.,similarity:Belongs to the peptidase M24A family.,
组织表达
Bone marrow,Placenta,Testis,
功能
catalytic activity:Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.,cofactor:Binds 1 sodium ion per subunit. The sodium ion has a structural role.,cofactor:Binds 2 cobalt ions per subunit.,cofactor:Binds 2 cobalt ions per subunit. The true nature of the physiological cofactor is under debate. The enzyme is also active with zinc, manganese or divalent iron ions.,function:Removes the amino-terminal methionine from nascent proteins.,function:Removes the amino-terminal methionine from nascent proteins. Required for normal progression through the cell cycle.,similarity:Belongs to the peptidase M24A family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.