BD-PE3528-ITGB3BP (19J4) Mouse Monoclonal antibody-现货抗体产品库武汉枢密脑科学技术有限公司

ITGB3BP (19J4) Mouse Monoclonal antibody

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产品基本信息

产品货号

BD-PE3528

产品名称

ITGB3BP (19J4) Mouse Monoclonal antibody

类别

常规抗体

基因名称

ITGB3BP

推荐应用

反应种属

Human

存储缓冲液

PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.

免疫原

Full length human recombinant protein of human ITGB3BP (NP_055103) produced in E.coli.

稀释度

WB 1:2000

预测分子量

20kDa

运输及保存条件

-20°C/1 year

宿主

Mouse

同种型

IgG1

背景介绍

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

期货

现货

纯化

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ITGB3BP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ITGB3BP(Cat# BD-PE3528). Positive lysates (100ug) and (20ug) can be purchased separately from OriGene.